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  1. Identifying modifiable risk factors of autism spectrum disorders (ASDs) may inform interventions to reduce financial burden. The infant/toddler gut microbiome is one such feature that has been associated with ...

    Authors: Hannah E. Laue, Kevin S. Bonham, Modupe O. Coker, Yuka Moroishi, Wimal Pathmasiri, Susan McRitchie, Susan Sumner, Anne G. Hoen, Margaret R. Karagas, Vanja Klepac-Ceraj and Juliette C. Madan
    Citation: Molecular Autism 2024 15:21
  2. Do autistic people share the same moral foundations as typical people? Here we built on two prominent theories in psychology, moral foundations theory and the empathizing–systemizing (E–S) theory, to observe t...

    Authors: Yeshaya David M. Greenberg, Rosemary Holt, Carrie Allison, Paula Smith, Robbie Newman, Theo Boardman-Pretty, Jonathan Haidt and Simon Baron-Cohen
    Citation: Molecular Autism 2024 15:20
  3. Most children with Autism Spectrum Disorder (ASD) have co-occurring language impairments and some of these autism-specific language difficulties are also present in their non-autistic first-degree relatives. O...

    Authors: Vardan Arutiunian, Megha Santhosh, Emily Neuhaus, Heather Borland, Chris Tompkins, Raphael A. Bernier, Susan Y. Bookheimer, Mirella Dapretto, Abha R. Gupta, Allison Jack, Shafali Jeste, James C. McPartland, Adam Naples, John D. Van Horn, Kevin A. Pelphrey and Sara Jane Webb
    Citation: Molecular Autism 2024 15:19
  4. Adolescence coincides with a dramatic rise in the onset of psychiatric conditions including depression. Depression symptoms may be particularly prevalent and impairing for youth with autism spectrum disorder (...

    Authors: Blythe A. Corbett, Rachael A. Muscatello, Trey McGonigle, Simon Vandekar, Christina Burroughs and Sloane Sparks
    Citation: Molecular Autism 2024 15:18
  5. Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental disorder that can significantly impact an individual’s ability to socially integrate and adapt. It’s crucial to identify key factors associated ...

    Authors: Yi Mao, Xindi Lin, Yuhan Wu, Jiayi Lu, Jiayao Shen, Shaogen Zhong, Xingming Jin and Jun Ma
    Citation: Molecular Autism 2024 15:17
  6. This meta-analysis aimed to explore the most robust findings across numerous existing resting-state functional imaging and voxel-based morphometry (VBM) studies on the functional and structural brain alteratio...

    Authors: Zixuan Guo, Xinyue Tang, Shu Xiao, Hong Yan, Shilin Sun, Zibin Yang, Li Huang, Zhuoming Chen and Ying Wang
    Citation: Molecular Autism 2024 15:16
  7. Clinicians diagnosing autism rely on diagnostic criteria and instruments in combination with an implicit knowledge based on clinical expertise of the specific signs and presentations associated with the condit...

    Authors: Eya-Mist Rødgaard, Borja Rodríguez-Herreros, Abderrahim Zeribi, Kristian Jensen, Valérie Courchesne, Elise Douard, David Gagnon, Guillaume Huguet, Sebastien Jacquemont and Laurent Mottron
    Citation: Molecular Autism 2024 15:15
  8. SH3 and multiple ankyrin repeat domains protein 3 (SHANK3) monogenic mutations or deficiency leads to excessive stereotypic behavior and impaired sociability, which frequently occur in autism cases. To date, t...

    Authors: Shanshan Wu, Jing Wang, Zicheng Zhang, Xinchen Jin, Yang Xu, Youwen Si, Yixiao Liang, Yueping Ge, Huidong Zhan, Li peng, Wenkai Bi, Dandan Luo, Mengzhu Li, Bo Meng, Qingbo Guan, Jiajun Zhao…
    Citation: Molecular Autism 2024 15:14
  9. Sleep disturbances are a common comorbidity to most neurodevelopmental disorders and tend to worsen disease symptomatology. It is thus crucial to understand mechanisms underlying sleep disturbances to improve ...

    Authors: Tanya Leduc, Hiba El Alami, Khadija Bougadir, Erika Bélanger-Nelson and Valérie Mongrain
    Citation: Molecular Autism 2024 15:13
  10. Glutamatergic synapse dysfunction is believed to underlie the development of Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) in many individuals. However, identification of genetic markers that...

    Authors: Sadhna Rao, Anastasiia Sadybekov, David C. DeWitt, Joanna Lipka, Vsevolod Katritch and Bruce E. Herring
    Citation: Molecular Autism 2024 15:12
  11. Structural differences exist in the brains of autistic individuals. To date only a few studies have explored the relationship between fetal brain growth and later infant autistic traits, and some have used fet...

    Authors: Ezra Aydin, Alex Tsompanidis, Daren Chaplin, Rebecca Hawkes, Carrie Allison, Gerald Hackett, Topun Austin, Eglė Padaigaitė, Lidia V. Gabis, John Sucking, Rosemary Holt and Simon Baron-Cohen
    Citation: Molecular Autism 2024 15:11
  12. A growing body of evidence suggests that immune dysfunction and inflammation in the peripheral tissues as well as the central nervous system are associated with the neurodevelopmental deficits observed in auti...

    Authors: Ryohei Takada, Michihiro Toritsuka, Takahira Yamauchi, Rio Ishida, Yoshinori Kayashima, Yuki Nishi, Mitsuru Ishikawa, Kazuhiko Yamamuro, Minobu Ikehara, Takashi Komori, Yuki Noriyama, Kohei Kamikawa, Yasuhiko Saito, Hideyuki Okano and Manabu Makinodan
    Citation: Molecular Autism 2024 15:10
  13. SHANK3 gene is a highly replicated causative gene for autism spectrum disorder and has been well characterized in multiple Shank3 mutant rodent models. When compared to rodents, domestic dogs are excellent animal...

    Authors: Feipeng Zhu, Qi Shi, Yong-hui Jiang, Yong Q. Zhang and Hui Zhao
    Citation: Molecular Autism 2024 15:9
  14. Autism spectrum disorder (ASD) is characterized by persistent social interaction impairments and is male-biased in prevalence. We have established naturally occurring low sociality in male rhesus monkeys as a ...

    Authors: Ozge Oztan, Laura A. Del Rosso, Sierra M. Simmons, Duyen K. K. Nguyen, Catherine F. Talbot, John P. Capitanio, Joseph P. Garner and Karen J. Parker
    Citation: Molecular Autism 2024 15:8
  15. Numerous interventions for irritability in autism spectrum disorder (ASD) have been investigated. We aimed to appraise the magnitude of pharmacological and non-pharmacological interventions for irritability in...

    Authors: Hangnyoung Choi, Jae Han Kim, Hee Sang Yang, Jong Yeob Kim, Samuele Cortese, Lee Smith, Ai Koyanagi, Elena Dragioti, Joaquim Radua, Paolo Fusar-Poli, Jae Il Shin, Keun-Ah Cheon and Marco Solmi
    Citation: Molecular Autism 2024 15:7
  16. Restricted repetitive behavior (RRB) is one of two behavioral domains required for the diagnosis of autism spectrum disorder (ASD). Neuroimaging is widely used to study brain alterations associated with ASD an...

    Authors: Bradley J. Wilkes, Derek B. Archer, Anna L. Farmer, Carly Bass, Hannah Korah, David E. Vaillancourt and Mark H. Lewis
    Citation: Molecular Autism 2024 15:6
  17. Helsmoortel–Van der Aa syndrome (HVDAS) is a rare genetic disorder caused by variants in the activity-dependent neuroprotector homeobox (ADNP) gene; hence, it is also called ADNP syndrome. ADNP is a multitasking ...

    Authors: Chuanhui Ge, Yuxin Tian, Chunchun Hu, Lianni Mei, Dongyun Li, Ping Dong, Ying Zhang, Huiping Li, Daijing Sun, Wenzhu Peng, Xiu Xu, Yan Jiang and Qiong Xu
    Citation: Molecular Autism 2024 15:5
  18. Gastrointestinal symptoms and inflammatory gastrointestinal diseases exist at higher rates in the autistic population. It is not clear however whether autism is associated with elevated gastrointestinal inflam...

    Authors: Nisha E. Mathew, Delyse McCaffrey, Adam K. Walker, Kylie-Ann Mallitt, Anne Masi, Margaret J. Morris and Chee Y. Ooi
    Citation: Molecular Autism 2024 15:4
  19. Autism spectrum disorder (henceforth autism) is a complex neurodevelopmental condition associated with differences in gray matter (GM) volume covariations, as reported in our previous study of the Longitudinal...

    Authors: Ting Mei, Alberto Llera, Natalie J. Forde, Daan van Rooij, Dorothea L. Floris, Christian F. Beckmann and Jan K. Buitelaar
    Citation: Molecular Autism 2024 15:3
  20. Autistic and non-autistic individuals often differ in how they perceive and show emotions, especially in their ability and inclination to infer other people’s feelings from subtle cues like facial expressions....

    Authors: Benedikt P. Langenbach, Dominik Grotegerd, Peter C. R. Mulders, Indira Tendolkar, Jasper van Oort, Fleur Duyser, Philip van Eijndhoven, Janna N. Vrijsen, Udo Dannlowski, Zarah Kampmann and Katja Koelkebeck
    Citation: Molecular Autism 2024 15:2
  21. To examine the relationship between social camouflage and mental health in Japanese autistic adults and make an international comparison with a sample from the UK.

    Authors: Fumiyo Oshima, Toru Takahashi, Masaki Tamura, Siqing Guan, Mikuko Seto, Laura Hull, William Mandy, Kenji Tsuchiya and Eiji Shimizu
    Citation: Molecular Autism 2024 15:1
  22. Emotion dysregulation (ED) is a core symptom of borderline personality disorder (BPD), whose aetiology has been attributed to biosocial factors. In autism spectrum condition (ASC), although ED is prevalent and...

    Authors: Doha Bemmouna, Amine Lagzouli and Luisa Weiner
    Citation: Molecular Autism 2023 14:47
  23. Previous studies showed that there is a positive association between mothers’ and children’s autistic traits. We also tested if this association is more pronounced in mothers with a higher pre-pregnancy body m...

    Authors: Novika Purnama Sari, Alexandros Tsompanidis, Rama J. Wahab, Romy Gaillard, Ezra Aydin, Rosemary Holt, Carrie Allison, Simon Baron-Cohen, Marinus H. van IJzendoorn and Pauline W. Jansen
    Citation: Molecular Autism 2023 14:46
  24. Repetitive and restricted behaviors and interests (RRBI) are core symptoms of autism with a complex entity and are commonly categorized into ‘motor-driven’ and ‘cognitively driven’. RRBI symptomatology depends...

    Authors: Aline Lefebvre, Nicolas Traut, Amandine Pedoux, Anna Maruani, Anita Beggiato, Monique Elmaleh, David Germanaud, Anouck Amestoy, Myriam Ly-Le Moal, Christopher Chatham, Lorraine Murtagh, Manuel Bouvard, Marianne Alisson, Marion Leboyer, Thomas Bourgeron, Roberto Toro…
    Citation: Molecular Autism 2023 14:45
  25. Autism spectrum disorder (ASD) encompasses a heterogeneous group with varied phenotypes and etiologies. Identifying pathogenic subgroups could facilitate targeted treatments. One promising avenue is investigat...

    Authors: Simon Maier, Kathrin Nickel, Thomas Lange, Georg Oeltzschner, Michael Dacko, Dominique Endres, Kimon Runge, Anke Schumann, Katharina Domschke, Michalis Rousos and Ludger Tebartz van Elst
    Citation: Molecular Autism 2023 14:44
  26. Autism spectrum disorders (ASD) are predominantly neurodevelopmental and largely genetically determined. However, there are human data supporting the idea that fever can improve symptoms in some individuals, b...

    Authors: Ana Belen Lopez-Rodriguez, Carol L. Murray, John Kealy, Clodagh Towns, Andrew Roche, Arshed Nazmi, Michelle Doran, John P. Lowry and Colm Cunningham
    Citation: Molecular Autism 2023 14:43
  27. Fragile X syndrome (FXS) is a leading cause of autism spectrum disorder (ASD) and resulted from a loss of the FMR1-encoded fragile X messenger ribonucleoprotein 1 (FMRP) protein due to large CGG repeat expansions...

    Authors: Shanshan Zhao, Xiangyu Jiang, Linkun Han, Yiru Jiang, Yong Wang, Jian Meng, Xiang Zhu, Xian Zhang, Hong Luo and Yun-wu Zhang
    Citation: Molecular Autism 2023 14:42
  28. There has been increasing evidence for atypical white matter (WM) microstructure in autistic people, but findings have been divergent. The development of autistic people in early childhood is clouded by the co...

    Authors: Xinyue Huang, Yating Ming, Weixing Zhao, Rui Feng, Yuanyue Zhou, Lijie Wu, Jia Wang, Jinming Xiao, Lei Li, Xiaolong Shan, Jing Cao, Xiaodong Kang, Huafu Chen and Xujun Duan
    Citation: Molecular Autism 2023 14:41
  29. Rett syndrome (RS) is a rare neurodevelopmental disorder characterized by mutations in the MECP2 gene. Patients with RS have severe motor abnormalities and are often unable to walk, use hands and speak. The prese...

    Authors: Daria Kostanian, Anna Rebreikina, Victoria Voinova and Olga Sysoeva
    Citation: Molecular Autism 2023 14:40
  30. Tuberous sclerosis complex (TSC) is an inherited neurocutaneous disorder caused by mutations in the TSC1 or TSC2 genes, with patients often exhibiting neurodevelopmental (ND) manifestations termed TSC-associated ...

    Authors: Inci S. Aksoylu, Pauline Martin, Francis Robert, Krzysztof J. Szkop, Nicholas E. Redmond, Srirupa Bhattacharyya, Jennifer Wang, Shan Chen, Roberta L. Beauchamp, Irene Nobeli, Jerry Pelletier, Ola Larsson and Vijaya Ramesh
    Citation: Molecular Autism 2023 14:39
  31. Sensory over-responsivity (SOR) is an impairing sensory processing challenge in autism spectrum disorder (ASD) which shows heterogenous developmental trajectories and appears to improve into adulthood in some ...

    Authors: Melis E. Cakar, Kaitlin K. Cummings, Susan Y. Bookheimer, Mirella Dapretto and Shulamite A. Green
    Citation: Molecular Autism 2023 14:38
  32. Many studies have reported that autism spectrum disorder (ASD) is associated with atypical structural and functional connectivity. However, we know relatively little about the development of these differences ...

    Authors: Christian O’Reilly, Scott Huberty, Stefon van Noordt, James Desjardins, Nicky Wright, Julie Scorah, Sara Jane Webb and Mayada Elsabbagh
    Citation: Molecular Autism 2023 14:37
  33. Autism spectrum disorders (ASD) are neurodevelopmental conditions accompanied by differences in brain development. Neuroanatomical differences in autism are variable across individuals and likely underpin dist...

    Authors: Lisa M. Berg, Caroline Gurr, Johanna Leyhausen, Hanna Seelemeyer, Anke Bletsch, Tim Schaefer, Charlotte M. Pretzsch, Bethany Oakley, Eva Loth, Dorothea L. Floris, Jan K. Buitelaar, Christian F. Beckmann, Tobias Banaschewski, Tony Charman, Emily J. H. Jones, Julian Tillmann…
    Citation: Molecular Autism 2023 14:36
  34. The poorer physical health of autistic adults compared to non-autistic adults has been highlighted by several epidemiological studies. However, research has so far been limited to specific geographical areas a...

    Authors: John H. Ward, Elizabeth Weir, Carrie Allison and Simon Baron-Cohen
    Citation: Molecular Autism 2023 14:35
  35. Many children and young people with autism spectrum disorder (ASD) display touch defensiveness or avoidance (hypersensitivity), or engage in sensory seeking by touching people or objects (hyposensitivity). Abn...

    Authors: Xue Li, Shishuai Hao, Shimin Zou, Xiaomeng Tu, Weixi Kong, Tian Jiang and Jie-Guang Chen
    Citation: Molecular Autism 2023 14:34
  36. Neuroimaging analyses of brain structure and function in autism have typically been conducted in isolation, missing the sensitivity gains of linking data across modalities. Here we focus on the integration of ...

    Authors: Lennart M. Oblong, Alberto Llera, Ting Mei, Koen Haak, Christina Isakoglou, Dorothea L. Floris, Sarah Durston, Carolin Moessnang, Tobias Banaschewski, Simon Baron-Cohen, Eva Loth, Flavio Dell’Acqua, Tony Charman, Declan G. M. Murphy, Christine Ecker, Jan K. Buitelaar…
    Citation: Molecular Autism 2023 14:32
  37. Differences in responding to sensory stimuli, including sensory hyperreactivity (HYPER), hyporeactivity (HYPO), and sensory seeking (SEEK) have been observed in autistic individuals across sensory modalities, ...

    Authors: Zachary J. Williams, Roseann Schaaf, Karla K. Ausderau, Grace T. Baranek, D. Jonah Barrett, Carissa J. Cascio, Rachel L. Dumont, Ekomobong E. Eyoh, Michelle D. Failla, Jacob I. Feldman, Jennifer H. Foss-Feig, Heather L. Green, Shulamite A. Green, Jason L. He, Elizabeth A. Kaplan-Kahn, Bahar Keçeli-Kaysılı…
    Citation: Molecular Autism 2023 14:31
  38. Prenatal exposure to maternal metabolic conditions associated with inflammation and steroid dysregulation has previously been linked to increased autism risk. Steroid-related maternal serum biomarkers have als...

    Authors: Deborah A. Bilder, Whitney Worsham, Scott Sullivan, M. Sean Esplin, Paul Burghardt, Alison Fraser and Amanda V. Bakian
    Citation: Molecular Autism 2023 14:30
  39. Deletion of exon 2 of the trimethyllysine hydroxylase epsilon (TMLHE) gene was identified in probands with autism spectrum disorder (ASD). TMLHE encodes the first enzyme in carnitine biosynthesis, N6-trimethyllys...

    Authors: Edgars Liepinsh, Baiba Svalbe, Gundega Stelfa, Solveiga Grinberga, Liga Zvejniece, Helgi B. Schiöth and Maija Dambrova
    Citation: Molecular Autism 2023 14:29
  40. Phelan–McDermid syndrome (PMS) is a neurodevelopmental disorder characterized by developmental delay, intellectual disability, and autistic-like behaviors and is primarily caused by haploinsufficiency of SHANK...

    Authors: Jessica Pagano, Silvia Landi, Alessia Stefanoni, Gabriele Nardi, Marica Albanesi, Helen F. Bauer, Enrico Pracucci, Michael Schön, Gian Michele Ratto, Tobias M. Boeckers, Carlo Sala and Chiara Verpelli
    Citation: Molecular Autism 2023 14:28
  41. Autism spectrum disorder (ASD) is a heritable condition related to brain development that affects a person’s perception and socialization with others. Here, we examined variability in the brain morphology in A...

    Authors: Yingying Xie, Jie Sun, Weiqi Man, Zhang Zhang and Ningnannan Zhang
    Citation: Molecular Autism 2023 14:27
  42. Septo-optic dysplasia (SOD) is a rare condition diagnosed in children with two or more of the following: hypopituitarism, midline brain abnormalities, and optic nerve hypoplasia. Children with SOD experience v...

    Authors: Amy Mann, Arameh Aghababaie, Jennifer Kalitsi, Daniel Martins, Yannis Paloyelis and Ritika R. Kapoor
    Citation: Molecular Autism 2023 14:26
  43. Quantitative autistic traits are common, heritable, and continuously distributed across the general human population. Patterns of autistic traits within families suggest that more complex mechanisms than simpl...

    Authors: Joseph P. Garner, Catherine F. Talbot, Laura A. Del Rosso, Brenda McCowan, Sreetharan Kanthaswamy, David Haig, John P. Capitanio and Karen J. Parker
    Citation: Molecular Autism 2023 14:25
  44. Autism spectrum disorder (ASD) is a set of highly heterogeneous neurodevelopmental diseases whose genetic etiology is not completely understood. Several investigations have relied on transcriptome analysis fro...

    Authors: Giovanni Spirito, Michele Filosi, Enrico Domenici, Damiano Mangoni, Stefano Gustincich and Remo Sanges
    Citation: Molecular Autism 2023 14:22
  45. Autism Spectrum Disorders (ASD) patients experience disturbed nociception in the form of either hyposensitivity to pain or allodynia. A substantial amount of processing of somatosensory and nociceptive stimulu...

    Authors: Florian Olde Heuvel, Najwa Ouali Alami, Oumayma Aousji, Esther Pogatzki-Zahn, Peter K. Zahn, Hanna Wilhelm, Dhruva Deshpande, Elmira Khatamsaz, Alberto Catanese, Sarah Woelfle, Michael Schön, Sanjay Jain, Stefanie Grabrucker, Albert C. Ludolph, Chiara Verpelli, Jens Michaelis…
    Citation: Molecular Autism 2023 14:21
  46. Neurodevelopmental disorders (NDDs) are heterogeneous conditions due to alterations of a variety of molecular mechanisms and cell dysfunctions. SETD5 haploinsufficiency leads to NDDs due to chromatin defects. Epi...

    Authors: Mattia Zaghi, Fabiana Longo, Luca Massimino, Alicia Rubio, Simone Bido, Pietro Giuseppe Mazzara, Edoardo Bellini, Federica Banfi, Paola Podini, Francesca Maltecca, Alessio Zippo, Vania Broccoli and Alessandro Sessa
    Citation: Molecular Autism 2023 14:20
  47. Genomic conditions can be associated with developmental delay, intellectual disability, autism spectrum disorder, and physical and mental health symptoms. They are individually rare and highly variable in pres...

    Authors: Nicholas Donnelly, Adam Cunningham, Sergio Marco Salas, Matthew Bracher-Smith, Samuel Chawner, Jan Stochl, Tamsin Ford, F. Lucy Raymond, Valentina Escott-Price and Marianne B. M. van den Bree
    Citation: Molecular Autism 2023 14:19

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