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Fig. 3 | Molecular Autism

Fig. 3

From: WDFY3 mutation alters laminar position and morphology of cortical neurons

Fig. 3

Wdfy3 loss leads to reduced dendritic arborization. A–C TdT and GFP immunofluorescence of individual neurons shows changes in dendritic arbor complexity. D, E Statistical analyses of Sholl profiles confirm significant changes of both deep and upper layer WT (+/+) or heterozygous neurons (+/lacZ) and lacZ/lacZ neurons. Significant deviations are indicated by the heatmaps adjacent to the x-axes of the Sholl profiles and p values resolved on the key on the right. Scale bar is 100 μm

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