Rats | Postnatal treatment of RSV | Prenatal treatment of RSV | ||||||
---|---|---|---|---|---|---|---|---|
Prenatal progestin exposure | ERβ mRNA level (%) | Social interaction time (seconds) | ERβ mRNA level (%) | Social interaction time (seconds) | ||||
Control | RSV | Control | RSV | Control | RSV | Control | RSV | |
Vehicle | 100 ± 9 | 111 ± 10 | 351 ± 27 | 369 ± 17 | 100 ± 11 | 91 ± 11 | 356 ± 24 | 340 ± 16 |
E2 | 94 ± 12 | 91 ± 13 | 369 ± 24 | 343 ± 16 | 89 ± 13 | 95 ± 9 | 341 ± 17 | 336 ± 19 |
P4 | 78 ± 10* | 119 ± 9 | 321 ± 17 | 339 ± 22 | 78 ± 8* | 106 ± 8 | 319 ± 22 | 369 ± 23 |
LNG | 54 ± 11* | 89 ± 12 | 259 ± 19* | 321 ± 19 | 61 ± 9* | 109 ± 11 | 263 ± 12* | 335 ± 17 |
MPA | 72 ± 13* | 115 ± 7 | 261 ± 24* | 351 ± 28 | 66 ± 12* | 92 ± 8 | 245 ± 11* | 361 ± 22 |
NES | 81 ± 11 | 91 ± 9 | 249 ± 20* | 298 ± 23* | 75 ± 8* | 111 ± 12 | 266 ± 18* | 350 ± 18 |
NET | 49 ± 8* | 106 ± 11 | 237 ± 16* | 326 ± 20 | 55 ± 10* | 106 ± 9 | 220 ± 25* | 348 ± 20 |
NETA | 67 ± 9* | 90 ± 9 | 286 ± 19* | 378 ± 14 | 72 ± 13* | 113 ± 11 | 301 ± 17* | 356 ± 25 |
NEN | 75 ± 8* | 113 ± 12 | 336 ± 26 | 361 ± 15 | 69 ± 14* | 78 ± 9* | 321 ± 25 | 336 ± 21 |
NGM | 85 ± 12 | 90 ± 8 | 279 ± 22* | 306 ± 22* | 78 ± 9* | 135 ± 11* | 291 ± 23* | 343 ± 24 |
OHPC | 59 ± 10 | 109 ± 11 | 268 ± 19* | 322 ± 21 | 63 ± 11* | 106 ± 12* | 287 ± 19* | 326 ± 22 |