22q11.2 duplication syndrome: elevated rate of autism spectrum disorder and need for medical screening

Table 3 Comparison of questionnaire data for participants with 22qDupNoASD, 22qDupASD, and idiopathic ASD

	SCQ Total	SRS total	Vineland-II socialization	Vineland-II composite
TDC
mean (SD)	1.7^a (1.8)	41.9^a (5.4)	114.0^a (12.7)	113.1^a (12.4)
n	57	73	57	57
DupNoASD
mean (SD)	14.1^ab (9.7)	68.1^ab (17.9)	88.3^a (20.2)	86.2^a (17.3)
n	13	14	14	14
DupASD
mean (SD)	26.8^b (7.8)	91.0^b (14.6)	72.8 (10.9)	75.5 (11.2)
n	5	5	4	4
ASD
mean (SD)	21.6 (5.3)	76.6 (15.1)	73.9 (12.4)	77.9 (11.6)
n	56	68	55	55

Significantly different scores (p < 0.05) between groups on each measure denoted as follows:
^aThis value is significantly different between the DupNoASD and Typically Developing Control groups
^bThis value is significantly different between the DupNoASD and DupASD groups
Abbreviations: ADHD attention-deficit/hyperactivity disorder, ADI-R Autism Diagnostic Interview-Revised, ADOS Autism Diagnostic Observation Schedule, ASD autism spectrum disorder, CASI-4R Child and Adolescent Symptom Inventory-4R, SCQ Social Communication Questionnaire, SRS Social Responsiveness Scale, TDC typically developing controls, Vineland-II Vineland Adaptive Behavior Scales-II

ISSN: 2040-2392