Dose | AN study 2 | AN study 3 | AN study 4 | Analysis for time trend doubly ordered r × c contingency tables Linear-by-linear association test | Exact Monte Carlo | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Response category | Response category | Response category | Test statistic | P (99% CI) | ||||||||||
0 | 4 | 8 | 12 | 0 | 4 | 8 | 12 | 0 | 4 | 8 | 12 | |||
Never ASD | 3 | 3 | 4 | 24 | 4 | 1 | 2 | 27 | 7 | 2 | 6 | 19 | −1.339 | 0.2 (0.19 to 0.21) |
ASD × 1-3 | 3 | 1 | 0 | 6 | 0 | 1 | 4 | 5 | 5 | 1 | 0 | 4 | −1.027 | 0.34 (0.33 to 0.36) |
ASD × 4 | 3 | 0 | 0 | 3 | 4 | 1 | 0 | 1 | 4 | 0 | 1 | 1 | −0.84 | 0.48 (0.46 to 0.49) |
Dose–response analysis doubly ordered r × c tables | Linear-by-linear association test | Linear-by-linear association test | Linear-by-linear association test | Stratified r × c contingency tables Cochran-Mantel-Haenszel test | ||||||||||
Test statistic | −2 | −3.22 | −2.437 | −4.385 | ||||||||||
Exact Monte Carlo P | 0.048 | 0.002 | 0.013 | 0 | ||||||||||
99% CI | 0.043 to 0.054 | 0.0008 to 0.003 | 0.01 to 0.016 | 0 to 0.0005 |