Table 3 Heritability estimates and their standard errors (se) based on contrasts to HealthABC and NGRC controls using genotypes from 391,425 SNPs but separating the AGP data into multiplex and simplex families for estimation
From: Common genetic variants, acting additively, are a major source of risk for autism
| Â | AGP multiplex | AGP simplex | ||||||
|---|---|---|---|---|---|---|---|---|
| Â | HealthABC | NGRC | HealthABC | NGRC | ||||
| Â | Estimate | se | Estimate | se | Estimate | se | Estimate | se |
Probands | 0.650 | 0.139 | 0.710 | 0.140 | 0.503 | 0.117 | 0.494 | 0.114 |
Mothers | 0.369 | 0.141 | 0.387 | 0.136 | 0.311 | 0.119 | 0.268 | 0.117 |
Fathers | 0.664 | 0.143 | 0.693 | 0.140 | 0.359 | 0.119 | 0.520 | 0.113 |
Pseudo controls | 0.497 | 0.146 | 0.524 | 0.140 | 0.323 | 0.120 | 0.438 | 0.117 |