Fig. 5
Dietary zinc supplementation normalises the altered paired-pulse ratio (PPR) in Tbr1+/− thalamic-LA synapses. A Representative traces of AMPAR-mediated EPSC PPR recorded from wildtype Tbr1+/+ mice (WT) and heterozygous mutant Tbr1+/− mice fed with normal or high dietary zinc. B The altered PPR in Tbr1+/− amygdalar thalamic-LA synapses is restored by the high zinc diet. (Sample size, neurons/animals: WT30ppm = 14/6, Tbr+/−30 ppm = 17/7, WT150ppm = 13/6, Tbr+/−150 ppm = 13/6). Each point represents individual neurons recorded in each experimental group. All data represent mean ± standard error of the mean, analysed using one-way analysis of variance with Tukey’s post hoc test. ns = not significant, **p < 0.01