Autism screening at 18 months of age: a comparison of the Q-CHAT-10 and M-CHAT screeners

Table 4 ASD screening performance comparisons

Row	Screen	Sensitivity	Specificity	PPV	NPV
1	M-CHAT-R n = 408	0.73 [0.61, 0.82] 2D \| 3D \| 4D	0.66 [0.61, 0.71] 2D \| 3D \| 4D	0.28 [0.22, 0.35] 2D \| 3D \| 4D	0.93 [0.89, 0.96] 2I \| 3D \| 4E
2	M-CHAT-R/F n = 368	0.36 [0.24, 0.49] 1D \| 3I \| 4D	0.89 [0.85, 0.92] 1D \| 3D \| 4D	0.36 [0.24, 0.49] 1D \| 3D \| 4I	0.89 [0.85, 0.92] 1I \| 3E \| 4I
3	Q-CHAT-10 n = 406	0.34 [0.23, 0.46] 1D \| 2I \| 4D	0.95 [0.92, 0.97] 1D \| 2D \| 4D	0.54 [0.39, 0.68] 1D \| 2D \| 4D	0.89 [0.85, 0.92] 1D \| 2E \| 4I
4	Q-CHAT-10-O n = 406	0.63 [0.50, 0.74] 1D \| 2D \| 3D	0.79 [0.74, 0.83] 1D \| 2D \| 3D	0.35 [0.27, 0.44] 1D \| 2I \| 3D	0.92 [0.89, 0.95] 1E \| 2I \| 3I

ISSN: 2040-2392

Row	Screen	Sensitivity	Specificity	PPV	NPV
1	M-CHAT-R n = 408	0.73 [0.61, 0.82] 2D \| 3D \| 4D	0.66 [0.61, 0.71] 2D \| 3D \| 4D	0.28 [0.22, 0.35] 2D \| 3D \| 4D	0.93 [0.89, 0.96] 2I \| 3D \| 4E
2	M-CHAT-R/F n = 368	0.36 [0.24, 0.49] 1D \| 3I \| 4D	0.89 [0.85, 0.92] 1D \| 3D \| 4D	0.36 [0.24, 0.49] 1D \| 3D \| 4I	0.89 [0.85, 0.92] 1I \| 3E \| 4I
3	Q-CHAT-10 n = 406	0.34 [0.23, 0.46] 1D \| 2I \| 4D	0.95 [0.92, 0.97] 1D \| 2D \| 4D	0.54 [0.39, 0.68] 1D \| 2D \| 4D	0.89 [0.85, 0.92] 1D \| 2E \| 4I
4	Q-CHAT-10-O n = 406	0.63 [0.50, 0.74] 1D \| 2D \| 3D	0.79 [0.74, 0.83] 1D \| 2D \| 3D	0.35 [0.27, 0.44] 1D \| 2I \| 3D	0.92 [0.89, 0.95] 1E \| 2I \| 3I