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Table 1 Participant demographics, showing means (± SD) and [range]

From: Functional MRI connectivity of children with autism and low verbal and cognitive performance

 

LVCP (n = 17)1

HVCP (n = 20)

NT (n = 19)2

Comparison

Male:female

14:3

15:5

14:5

–

Age (years)

12.26 (± 3.34)

[7–17]

12.64 (± 2.87)

[7–17]

11.76 (± 2.61)

[7–17]

LVCP = HVCP = NT

IQ composite score3

(standard score)

54.00 (± 17.50)

[25–77]

106.85 (± 13.64)

[85–130]

111.76 (± 13.05)

[85–134]

LVCP < HVCP = NT

Verbal score4,5

(standard score)

47.5 (± 20.09)

[25–78]

103.63 (± 11.73)

[85–126]

114.84 (± 13.8)

[94–140]

LVCP < HVCP = NT

ADOS-2 Modules administered

Module 1 n = 5

Module 2 n = 8

Module 3 n = 4

Module 3 n = 16

Module 4 n = 4

  

ADOS-2 comparison score6

7.94 (± 1.52)

[4–10]

7.35 (± 2.01)

[4–10]

–

LVCP = HVCP

  1. LVCP low verbal and cognitive performance with autism, HVCP high verbal and cognitive performance with autism, NT neurotypical. 1Original group of 22 less 4 with unsuccessful scans and 1 with excess motion. 2Original group of 20 less 1 with excess motion. 3 IQ composite is the Differential Ability Scales-II General Conceptual Ability or Wechsler Full-Scale IQ. 4Verbal scores reflect Vocabulary subtest or Verbal index scores. Two scores from LVCP group were not obtained (verbal level estimated by ADOS Module 1 for adolescent and another with overall composite score of 49). The verbal score was not obtained for one individual in the HVCP group, IQ composite score = 88). 5Verbal scores were highly correlated with overall IQ scores, r = .945, p < .001. 6Autism Diagnostic Observation Scale, Second Edition, Calibrated Severity Score (comparison score), which is from a 10-point scale, where 0 = minimal-to-no evidence of autism, 10 = high evidence of autism. For all comparisons, significant differences indicate p < .001 and no significant differences indicate p > .05