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Fig. 3 | Molecular Autism

Fig. 3

From: Brain hyperserotonemia causes autism-relevant social deficits in mice

Fig. 3

Recovery of behavioral abnormalities by dietary tryptophan depletion in Sert HZ and KO mice. a Experimental protocol. b Extracellular 5-HT levels in the striatum. c Locomotor activity over 60 min in the open field test. d Active interaction time over 10 min in the social interaction test. The data are expressed as mean ± SEM. *P < 0.05, **P < 0.01, Welch’s t test (b). *P < 0.05, **P < 0.01, two-way ANOVA followed by Fisher’s PLSD test (c, d)

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