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Fig. 5 | Molecular Autism

Fig. 5

From: 17-β estradiol increases parvalbumin levels in Pvalb heterozygous mice and attenuates behavioral phenotypes with relevance to autism core symptoms

Fig. 5

Performance of PV+/+, PV+/−, and PV−/− mice in the marble-burying test. a Total number of buried marbles in vehicle-treated and E2-treated mice; asterisks represent *p < 0.05. b Numerical difference within the same genotype groups between E2-treated and vehicle-treated mice. Negative values below “0” indicate attenuation of repetitive, ritualistic behavior; values above “0” indicate an E2-mediated increase of marble-burying behavior, i.e., an increase in ASD-associated behavior

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Molecular Autism

ISSN: 2040-2392