Fig. 6
From: Impairment of social behaviors in Arhgef10 knockout mice
Increased amine levels in the brains of Arhgef10 knockout mice. The frontal cortex, striatum, hippocampus, and amygdala were dissected from mice brains for HPLC analysis. a The content of NE was elevated in both the frontal cortex and the amygdala in Arhgef10 knockout mice. b The content of 5-HT in the frontal cortex and amygdala was significantly increased in Arhgef10 knockout mice. c The content of dopamine was increased in the striatum of Arhgef10 knockout mice. d, e There was no significant difference in the content of 5-HIAA or DOPAC (metabolites) between WT and Arhgef10 −/− mice. The bar graph shows the mean ± SEM (n = 6 for each); *p < 0.05 compared with WT