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Table 5 Dysmorphisms in individuals with FOXP1 syndrome

From: Prospective investigation of FOXP1 syndrome

Dysmorphisms

S1

S2

S3

S4

S5

W1

W2

W3

W4

Total (%)

Height in cm (percentile)

Short Stature

112 (35.9)

−

160.5 (35.6)

−

146 (57.4)

−

132.5 (2.6)

+

124 (27.7)

−

165.4 (24.4)

−

131 (2.4)

+

130 (14)

−

n/a

2/8 (25%)

Macrocephaly (percentile)

−(97)

+(> 99)

−(75)

+(> 99)

+(> 99)

−(83)

−(63)

+(> 99)

n/a

4/8 (50%)

Broad nasal bridge

+

+

+

+

+

–

+

–

n/a

6/8 (75%)

Prominent forehead

+

+

–

+

+

–

+

+

n/a

6/8 (75%)

Bulbous nose

+

+

+

+

+

–

–

–

n/a

5/8 (63%)

High arched palate

+

+

+

–

+

–

–

–

n/a

4/8 (50%)

Hypertelorism

–

+

–

+

+

–

+

–

n/a

4/8 (50%)

Clinodactyly

–

–

–

+

+

+

–

+

n/a

4/8 (50%)

Epicanthal folds

–

–

–

+

–

+

+

–

n/a

3/8 (38%)

Malocclusion

+

+

–

+

–

–

–

–

n/a

3/8 (38%)

Long philtrum

–

+

+

–

+

–

–

–

n/a

3/8 (38%)

Thick vermillion

–

+

+

+

–

–

–

–

n/a

3/8 (38%)

Single palmar crease

+

–

–

–

–

+

–

–

n/a

2/8 (25%)

Pectus excavatum

+

–

+

–

–

–

–

–

n/a

2/8 (25%)

Frontal hair upsweep

+

–

–

–

–

–

–

+

n/a

2/8 (25%)

Ptosis

–

+

–

–

–

–

–

–

n/a

1/8 (13%)

Pointed chin

–

–

–

–

+

–

–

–

n/a

1/8 (13%)

Bicuspid uvula

–

–

–

–

+

–

–

–

n/a

1/8 (13%)

Partial syndactyly 2nd and 3rd toes

+

–

–

–

–

–

–

–

n/a

1/8 (13%)

Deep set eyes

+

–

–

–

–

–

–

–

n/a

1/8 (13%)

Scoliosis

–

–

–

+

–

–

–

–

n/a

1/8 (13%)

Short neck

–

–

–

+

–

–

–

–

n/a

1/8 (13%)

Sacral dimple

–

–

+

–

–

–

–

–

n/a

1/8 (13%)

Hyperflexibility

+

–

–

–

–

–

–

–

n/a

1/8 (13%)

Long eyelashes

–

–

–

+

–

–

–

–

n/a

1/8 (13%)

Total number of dysmorphic features

11

10

7

13

10

3

5

4

n/a

7.9 ± 3.6

  1. n/a information not available