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Fig. 5 | Molecular Autism

Fig. 5

From: A novel system for tracking social preference dynamics in mice reveals sex- and strain-specific characteristics

Fig. 5

Parameters of behavioral dynamics in the SP and SNP tests. a Distribution of the tested mice according to the total number of transitions made by each subject in the SP test. Dashed line marks the mean value. b As in a, for the SNP test. c A significant positive correlation (rĀ =Ā 0.51, pā€‰<ā€‰0.001, Pearsonā€™s correlation) was found between the number of transitions made by each subject during the SP and SNP tests. d No correlation was found between the RDI and total number of transitions during the SP test. e A significant negative correlation (rĀ =Ā āˆ’ā€‰0.42, pā€‰<ā€‰0.01) was found between the RDI and total number of transitions during the SNP test, suggesting a link between the number of transitions made by the subject and its recognition of the familiar social stimulus. f Distribution of the total time spent by the subject during the SP test on intervals between consecutive investigation bouts directed towards each stimulus, according to the length of interval. g As in f, for the SNP test. h A significant negative correlation (rĀ =Ā āˆ’ā€‰0.9, pā€‰<ā€‰0.05) was found between the RDI calculated according to the difference in investigation time (higher for the preferred stimulus) and the RDI calculated according to the difference in prolonged intervals (lower for the preferred stimulus, in the SP test). i As in h, for the SNP test (rĀ =Ā āˆ’ā€‰0.92, pā€‰<ā€‰0.001). ***pā€‰<ā€‰0.001, **pā€‰<ā€‰0.01, *pā€‰<ā€‰0.05

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