Table 1 Study design and sample size of the contributing ASD collections. For some collections, more than one genotyping panel was used or the study design differed, i.e., trios or case-control; in such cases, the sample was split into ‘sets’ based on genotyping array and design

Autism Center of Excellence Network (ACE)

Trios

372

372^a

3.1:1

82.1

Autism Genetic Resource Exchange (AGRE)

[1]

Trios

572

572^a

3.5:1

100.0

[2]

Trios

1045

1045^a

3.9:1

86.1

Autism Genome Project (AGP)

[1]

Trios

1259

1259^a

5.4:1

95.9

[2]

Trios

941

941^a

8.6:1

84.4

Finnish Case-Control ASD Collection

CaCo

159

526

3.3:1

99.7

NIMH Repository and Montreal/Boston (MonBos) Collection

Trios

117

117^a

4.1:1

95.5

Population-Based Autism Genetics and Environment Study (PAGES)

CaCo

305

1200

2.2:1

100.0

Simons Simplex Collection (SSC)

[1]

Trios

396

396^a

7.1:1

86.2

[2]

Trios

617

617^a

6.2:1

84.7

[3]

Trios

804

804^a

5.9:1

82.0

[4]

Trios

372

372^a

7.5:1

87.8

Weiss Laboratory Autism Collection

[1]

CaCo

331

249

7.2:1

100.0

[2]

Trios

97

97^a

1.2:1

100.0

7387

8567

4.9:1

90.8