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Fig. 3 | Molecular Autism

Fig. 3

From: Vitamin D treatment during pregnancy prevents autism-related phenotypes in a mouse model of maternal immune activation

Fig. 3

Marble burying behavior in juvenile offspring who were exposed to prenatal immune challenge (POL) or prenatal vitamin D treatment (VitD). a Marble burying was markedly reduced in POL/VEH mice relative to all other groups, suggesting that MIA alters stereotyped behavior in prepubertal offspring (*P < 0.05). VitD co-administration completely blocked this MIA-induced alteration in marble burying (*P < 0.05). b An examination of total distance showed MIA treated mice moved significantly more in this test regardless of VitD co-treatment (*P < 0.05). All values are mean ± SEM (n = 8)

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