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Table 4 Clusters of significant differences in cortical morphometry between TD and ASD

From: Cortical morphological markers in children with autism: a structural magnetic resonance imaging study of thickness, area, volume, and gyrification

Measure

Cluster

Size (mm2)

N vertices

p cluster

t peak

X Tal

Y Tal

Z Tal

Peak region

Age-by-diagnosis interaction effects (df = 97)

 Thickness

1

2965.01

5623

0.0002

4.334

50.3

−56.7

8.2

R middle temporal

 

2

2864.20

6405

0.0002

3.867

19.0

−64.6

43.5

R superior parietal

 

3

2558.92

6841

0.0005

4.743

14.6

−14.4

37.4

R posterior cingulate

 

4

1878.90

3472

0.0080

3.750

26.5

36.7

18.1

R rostral middle frontal

 

5

1457.79

2597

0.0375

3.885

−33.0

9.4

28.1

L caudal middle frontal

 Volume

1

2370.44

4619

0.0002

4.677

48.1

−33.0

4.5

R bankssts

 

2

1912.43

4245

0.0015

3.658

18.8

−64.9

43.6

R superior parietal

 Gyrification

1

2662.70

6064

0.0001

3.361

−27.8

−49.8

48.5

L superior parietal

 

2

4359.25

6920

0.0001

3.277

20.2

58.7

8.9

R rostral middle frontal

 

3

2141.64

4528

0.0001

3.243

35.6

8.4

21.8

R pars opercularis

 

4

995.32

2324

0.0013

3.586

−17.2

−13.4

57.9

L precentral

 

5

824.99

1881

0.0067

3.047

64.9

−20.1

2.4

R superior temporal

Between-group differences (independent of Age) (df = 98)

 Gyrification

1

2275.23

3856

0.0001

3.862

38.9

−78.1

20.8

R inferior parietal

 

2

1625.12

2784

0.0001

3.820

51.2

−13.5

−30.5

R inferior temporal

 

3

4186.02

7911

0.0001

3.645

−13.5

−48.8

6.2

L isthmus cingulate

 

4

1738.54

2122

0.0001

3.644

10.4

−91.7

−1.7

R lingual