Table 2 Top five SNPs from tier 2 analysis: all chromosome X SNPs
From: The female protective effect in autism spectrum disorder is not mediated by a single genetic locus
AGRE discovery (208 cases, 151 controls) | SSC replication (207 cases, 676 controls) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
SNP | Allele 1/allele 2 | Affected allele 1 frequency (%) | Unaffected allele 1 frequency (%) | Odds ratio | P value | Corrected P value | Affected allele 1 frequency (%) | Unaffected allele 1 frequency (%) | Odds ratio | P value |
Predicted | . | 97.0 | <24.3 | >88 | ≤1×10−8 | ≤0.05 | 97.0 | <24.3 | >88 | ≤1×10−8 |
rs2429799 | A/G | 21.2 | 7.3 | 2.90 | 0.0003 | 1.0 | . | . | . | . |
rs5932245 | A/G | 97.1 | 87.4 | 1.11 | 0.0004 | 1.0 | 54.1 | 55.0 | 0.98 | 0.9645 |
rs878252 | G/A | 31.7 | 15.9 | 2.00 | 0.0006 | 1.0 | 29.0 | 25.6 | 1.13 | 0.1699 |
rs5928065 | G/A | 94.7 | 84.1 | 1.13 | 0.0008 | 1.0 | 88.4 | 93.3 | 0.95 | 0.5674 |
rs7063248 | G/A | 73.4 | 57.6 | 1.27 | 0.0017 | 1.0 | 97.1 | 96.6 | 1.01 | 0.1885 |