SNP ID
|
MAF (cases)
|
MAF (controls)
|
SNP association analysis in our sample
|
SNP association analysis in the PGC database
|
---|
OR
|
X
2
|
P
value
|
OR
|
SE
|
P
value
|
---|
rs3848173 | 0.2288 | 0.1667 | 1.484 | 4.768 | 0.029 | Â | Â | Â |
rs17225178 | 0.1966 | 0.1173 | 1.842 | 9.773 |
0.001771
| 1.115 | 0.0433 | 0.0121 |
- Nominally significant P values after genetic association analysis between 34 SNPs in ARNT2 and AS in our sample are reported (α = 0.05). Significant P value after Bonferroni correction for total number of SNPs is written in bold and italicized (α = 0.0024). Major allele is the reference allele for the estimated OR. Results of genetic association analysis between rs17225178 and ASC in the PGC database are also reported. AS, Asperger Syndrome; ASC, Autism Spectrum Conditions; MAF, minor allele frequency; OR, odds ratio; PGC, Psychiatric Genomics Consortium; SE, standard error for the odds ratio; SNP, single nucleotide polymorphism.