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Table 5 Correlation of Rora and target gene expression levels in the frontal cortex of adult male and female mice

From: Investigation of sex differences in the expression of RORA and its transcriptional targets in the brain as a potential contributor to the sex bias in autism

Cyp19a1 vs. Rora

All

Males

Females

Correlation coefficient

0.63

0.92

-0.97

P val (2-tailed)

0.18

0.25

0.16

R2

0.4

0.85

0.94

A2bp1 vs. Rora

All

Males

Females

Correlation coefficient

0.68

0.99

0.13

P val (2-tailed)

0.13

0.06

0.92

R2

0.46

0.99

0.02

Itpr1 vs. Rora

All

Males

Females

Correlation coefficient

0.59

0.96

-0.40

P val (2-tailed)

0.22

0.18

0.74

R2

0.35

0.92

0.16

Nlgn1 vs. Rora

All

Males

Females

Correlation coefficient

0.96

0.95

0.45

P val (2-tailed)

0.002

0.2

0.7

R2

0.92

0.9

0.2

  1. The correlation coefficients, P values, and R2 values are shown for Rora expression and that of Cyp19a1, A2bp1, Itpr1, and Nlgn1. Three male and three female mice were used for each group.