From: A pilot controlled trial of insulin-like growth factor-1 in children with Phelan-McDermid syndrome
Adverse events | IGF-1 | Placebo |
---|---|---|
Constipation | 4 | 3 |
Sedation | 1 | 0 |
Decreased appetite | 2 | 3 |
Periobital/facial swelling | 1 | 0 |
Diarrhea | 1 | 2 |
URTIa | 5 | 5 |
Sleep Disturbance | 7 | 2 |
Increased appetite | 4 | 0 |
Mood changes/irritability | 4 | 2 |
Increased thirst | 1 | 0 |
Increased phlegm | 1 | 0 |
Teeth grinding | 1 | 0 |
Cough | 1 | 2 |
Hand flapping | 1 | 0 |
Increased bowel movements | 1 | 0 |
Increased chewing/biting | 1 | 0 |
Decreased visual acuity | 1 | 0 |
Lethargy/decreased energy | 1 | 1 |
Cooler body temperature/sweating | 1 | 0 |
Runny nose/congestion | 1 | 1 |
Gait changes/fell | 1 | 2 |
Stomach virus | 1 | 1 |
Anxiety | 0 | 2 |
Increased urine frequency | 2 | 0 |
Fever | 3 | 3 |
Increased energy | 1 | 0 |
Gagging | 1 | 0 |
Increased thirst | 0 | 1 |
Conjunctivitis | 1 | 0 |
Erythema/swollen eyes | 1 | 0 |
Vomiting | 1 | 1 |
Rash | 3 | 0 |
Nose swelling | 1 | 0 |
Warmer body temperature | 1 | 0 |
Hair loss | 1 | 0 |
Increased aggression | 1 | 0 |
Hypoglycemiab | 7 | 3 |