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Table 1 Sequence alignment and variant detection methods

From: Identification of rare DNA sequence variants in high-risk autism families and their prevalence in a large case/control population

 

Alignment and assembly

Sequence variant detection

Method 1

Bowtie

Maq

Method 2

MOSAIK

GigaBayes

Method 3

CLC Bio Genomics Workbench (CLC Bio Inc.)

CLC Bio Genomics Workbench

  1. (CLC Bio Inc., Cambridge, MA, USA).