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Figure 6 | Molecular Autism

Figure 6

From: Identification of rare DNA sequence variants in high-risk autism families and their prevalence in a large case/control population

Figure 6

Segregation of multiple variants including a sequence variant in AKAP9 and a copy number variant in NRXN1 in a multi-generation pedigree. Pedigree 5 has nine children affected with autism. A link between this pedigree and another high-risk autism pedigree is indicated by the blue box. Sequence variants identified in the family are shown in the black boxes. CNVs identified in four individuals [27] are shown in red boxes. Pedigree symbols are described in the legend for Figure 2. Odds ratios for the variants observed in the case/control study are shown in parentheses. Variants with no odds ratio were observed only in high-risk families. All family members were tested for all variants unless no DNA was available. Individuals with no available DNA are indicated.

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Molecular Autism

ISSN: 2040-2392