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Table 1 Demographic characteristics of postmortem brain samples

From: Dysregulation of estrogen receptor beta (ERβ), aromatase (CYP19A1), and ER co-activators in the middle frontal gyrus of autism spectrum disorder subjects

Variable

Control

ASD

Age (years)

11.70 ± 1.584

11.80 ± 1.609

PMI (h)

14.46 ± 2.171

19.00 ± 2.776

Sex (F/M)

1/12

0/13

Storage (days)

4287 ± 638.7

2829 ± 397.7

RIN

5.55 ± 0.71

6.84 ± 0.53

pH

5.95 ± 0.06

6.11 ± 0.07

Manner of death

Drowning (3), Vehicle accident (4), Hanging/suicide (2), Cardiovascular complication (1), TSS (1), Multisystem failure (1), Anaphylaxis (1)

Drowning (6)

Vehicle accident (1)

Cardiovascular complication (2)

Cancer (1)

Hemorrhage (2)

Diabetic ketoacidosis (1)

Medications*

Yes (1) (Concerta, Clonidine)

Yes (4) (Zyprexa (1), Reminyl (1), Naltrexone (1), Risperdal (2), Luvox (1), Clonidine (1), Insulin (1))

No (12)

No (9)

  1. ASD, Autism spectrum disorder; F, Female; M, Male; PMI, Postmortem interval; RIN, RNA integrity; TSS, Toxic shock syndrome. Values are Mean ± SE. *Note that some individuals took multiple medications.