Serum proteomic analysis identifies sex-specific differences in lipid metabolism and inflammation profiles in adults diagnosed with Asperger syndrome

Table 2 Identification of analytes altered between individuals with Asperger syndrome (AS) (n = 30) and controls (n = 29) using multiplex immunoassay analysis

	P-value	FDR	Ratio
Neuronal cell adhesion molecule	0.022	0.19	1.40
IL-5	0.007	0.13	1.28
CD40	0.008	0.13	1.21
Cortisol	0.003	0.088	1.20
TNF-alpha	0.024	0.19	1.20
IL-7	0.012	0.15	1.18
BDNF	0.015	0.17	1.16
Sortilin	0.007	0.13	1.15
Serum glutamic-oxaloacetic transaminase	0.003	0.088	0.82
Apolipoprotein A1	0.018	0.19	0.79
Immunoglobulin M	0.002	0.088	0.73
HB-epidermal growth factor	0.002	0.088	0.70
Eotaxin-3	0.048	0.29	0.60
Ferritin	0.010	0.14	0.60
Fatty acid binding protein	0.030	0.20	0.50
Growth hormone	0.029	0.20	0.39

The results are adjusted for age and BMI. FDR = false discovery rate. Ratio = AS/control. Grey shading indicates these proteins had a significant sex-diagnosis interaction.

ISSN: 2040-2392