Table 1 Demographic and clinical data of patients with autism and controls
From: Neuropathology of the posteroinferior occipitotemporal gyrus in children with autism
Case | Diagnosis | Age (years) | Sex | Hemisphere | Cut/mounted thickness (μm) | PMI (hours) | BW (grams) | Cause of death | Relevant clinical information | ADI-R |
|---|---|---|---|---|---|---|---|---|---|---|
425-02 | A1 | 4 | M | L | 200/178.5 | 30 | 1,160 | Drowning | Symptoms present at two years | 14, 10 (NV), 3 |
Frequent tantrums and self-injurious behavior | ||||||||||
Used parents’ hand to reach objects, echolalia, tendency to walk on his tiptoes | ||||||||||
Stereotypic play | ||||||||||
15-763-95 | C1 | 4 | M | L | 600/574.1 | 3 | 1,380 | Myocardial infarct | No known disorder | – |
425-02 | A2 | 4 | M | R | 200/165.6 | 30 | 1,160 | Drowning | Symptoms present at two years | 14, 10 (NV), 3 |
Frequent tantrums and self-injurious behavior | ||||||||||
Used parents’ hand to reach objects, echolalia, tendency to walk on his tiptoes | ||||||||||
Stereotypic play | ||||||||||
15-763-95 | C2 | 4 | M | R | 600/575.6 | 3 | 1,380 | Myocardial infarct | No known disorder | – |
M6-06 | A3 | 7 | M | R | 200/176.6 | 25 | 1,610 | Drowning | Regression after first seizure at 14Â months | 29. 14 (NV), 3 |
No spontaneous meaningful language | ||||||||||
Used parents’ hands as a tool | ||||||||||
No reciprocal social smiling or eye contact | ||||||||||
Stereotypic play | ||||||||||
Psychiatric and developmental disorders on maternal side | ||||||||||
M15-06 | C3 | 7 | M | R | 200/190.2 | 12 | 1,240 | Drowning | No known disorder | – |
M5-03 | A4 | 8 | M | R | 200/182.1 | 22.2 | 1,570 | Rhabdomyo-sarcoma | Symptoms present at three years | 19, 14 (V), 4 |
Engaged in repetitive play, jumping up and down on his tiptoes, echolalia | ||||||||||
Cancer diagnosis at age six | ||||||||||
Abnormal EEG | ||||||||||
M3-04 | C4 | 8 | F | R | 200/182.8 | 20 | 1,222 | Multiple injuries | No known disorder | – |
427-02 | A5 | 11 | F | L | 200/177.9 | 13 | 1,460 | Drowning | Tonic-clonic seizures | 22, 14 (V), 3 |
Developmental, intellectual, and language delays | ||||||||||
Poor eye contact | ||||||||||
Poor social interaction | ||||||||||
M9-03 | C5 | 14 | M | R | 200/188.8 | 20 | 1,464 | Electrocution | No known disorder | – |
M5-05 | A6 | 17 | F | L | 200/153.6 | 25 | 1,580 | Cardiac arrest | Difficulty with reciprocal social interaction | 29, 14 (NV), 3 |
Appropriate emotional response to her family, but not to others | ||||||||||
Non-social use of language | ||||||||||
Stereotypic behaviors | ||||||||||
M16-06 | C6 | 15 | F | R | 200/174.6 | 9 | 1,250 | Multiple injuries | No known disorder | – |
M1-03 | A7 | 21 | F | R | 200/263.6 | 50 | 1,108 | Obstructive pulmonary disease | Seizures | 21, 11 (NV), 3 |
Engaged in repetitive play, bouncing up and down on her tiptoes, echolalia | ||||||||||
Abnormal EEG | ||||||||||
M1-07 | C7 | 20 | F | R | 200/187.1 | 9 | 1,340 | Multiple injuries | No known disorder | – |