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Table 2 Sex subset-specific linkage signals

From: Replication of linkage at chromosome 20p13 and identification of suggestive sex-differential risk loci for autism spectrum disorder

Locus

Subgroup

Stage 1 sample peak LOD

Combined sample peak LOD

Gene at suggestive linkage peak

Sex-differential linkage empirical P-value

1p31.3

MO

2.98

-----

NFIA

<0.01

MO

-----

2.55

NFIA

<0.0005

4q26

MO

2.41

1.28

SYNPO2

NS

6q27

MO

2.86

2.07

MLLT4

NS

8p21.2

FC

2.67

1.42

EBF2

<0.05

8p12

FC

2.37

1.34

NRG1

<0.005

  1. Bold type indicates significant sex-differential linkage signals with empirical P ≤ 0.05. FC, female-containing; LOD, logarithm of odds; MO, male-only; NS, not significant.
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Molecular Autism

ISSN: 2040-2392