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Table 1 Phenotype measures and participant information

From: Genetic variation in GABRB3 is associated with Asperger syndrome and multiple endophenotypes relevant to autism

Participants

Case–control

AQa

EQ

SQ-R

RMETb

EFTb

MRTb

Cases

Controlsa

Numbers

        

  Total

118

412

412

413

414

245

245

245

  Male

74

185

185

209

210

122

122

122

  Female

44

227

227

204

204

123

123

123

Trait score, mean ± SD

      

  Overall

35.6 ± 8.9c

14.9 ± 5.0c

14.9 ± 5.0

41.5 ± 12.3

60.3 ± 20.6

27.1 ± 3.2

11.6 ± 1

16.8 ± 2.6

  Male

35.1 ± 8.7c

16.0 ± 4.4c

16.0 ± 4.4

36.8 ± 12.4

63.9 ± 20.0

27.06 ± 3.2

11.7 ± 0.6

17.4 ± 2.1

  Female

36.6 ± 8.8c

13.9 ± 5.1c

13.9 ± 5.1

45.6 ± 12.3

56.5 ± 20.4

27.1 ± 3.2

11.6 ± 1.2

16.1 ± 2.9

  Range

7 to 50

2 to 23

2 to 23

2 to 24

11 to 139

17 to 34

2 to 12

7 to 20

  1. Abbreviations: AQ, Autism Spectrum Quotient; EFT, Embedded Figures Test; EQ, Empathy Quotient; MRT, Mental Rotation Test; RMET, Reading the Mind in the Eyes Test; SQ-R, Systemizing Quotient, Revised.
  2. aThe same individuals participated in the case–control and AQ quantitative trait studies.
  3. bThe same individuals participated in REMT, EFT, and MRT.
  4. cTrait scores for case–control study are the Adult Autism Spectrum Quotient scores.