Table 1 Demographic data for individuals with autism and controls
Case | Dx | Sex | Age | PMI (hrs) | Ethnicity | Medication history | Cause of death | Seizure | ID | Side of brain | Brain region |
|---|---|---|---|---|---|---|---|---|---|---|---|
UMB-4670 | Control | M | 4 | 17 | Caucasian | None | Commotio cordis | No | No | Unknown | BA9, Vermis |
UMB-4898 | Control | M | 7 | 12 | Caucasian | Methylphenidate; clonidine | Drowning | No | No | Unknown | Vermis |
UMB-1674 | Control | M | 8 | 36 | Caucasian | None | Drowning | No | No | Unknown | BA9, Vermis |
UMB-4787 | Control | M | 12 | 15 | African American | Montelukast; albuteral; prednisone, loratadine | Asthma | No | No | Unknown | BA9, Vermis |
UMB-1823 | Control | M | 15 | 18 | Caucasian | None | MVA | No | No | Unknown | BA9, Vermis |
AN17425 | Control | M | 16 | 26.16 | Unknown | None | Heart attack | No | No | Left | BA9 |
AN15105 | Control | M | 18 | 19.83 | Unknown | None | Unknown | No | No | Unknown | BA9, Vermis |
AN03217 | Control | M | 19 | 18.58 | Caucasian | None | Pneumonia | No | No | Left | BA9 |
UMB-1846 | Control | F | 20 | 9 | Caucasian | None | MVA | No | No | Unknown | BA9, Vermis |
AN07176 | Control | M | 21 | 29.91 | Unknown | None | MVA | No | No | Left | BA9 |
AN14368 | Control | M | 22 | 24.2 | Unknown | None | Unknown | No | No | Left | BA9 |
AN19760 | Control | M | 28 | 23.25 | Unknown | None | Unknown | No | No | Left | BA9 |
AN15566 | Control | F | 32 | 28.92 | Unknown | None | Unknown | No | No | Left | BA9, Vermis |
UMB-1169 | Control | M | 33 | 27 | African American | Metoclopramide; loratadine | Dilated cardiomyopathy (morbid obesity) | No | No | Unknown | BA9, Vermis |
UMB-1376 | Control | M | 37 | 12 | African American | None | ASCVD | No | No | Unknown | BA9, Vermis |
AN15151 | Control | M | 41 | 30.4 | Unknown | None | Heart attack | No | No | Unknown | BA9, Vermis |
AN19440 | Control | F | 50 | 20.25 | Unknown | None | Heart attack | No | No | Unknown | BA9 |
AN12240 | Control | M | 51 | 4.75 | Caucasian | None | Heart attack | No | No | Right | BA9 |
AN13295 | Control | M | 56 | 22.12 | Unknown | None | Unknown | No | No | Right | BA9 |
AN08873 | Autism | M | 5 | 25.5 | Caucasian | None | Drowning | No | No | Left | BA9 |
AN13872 | Autism | F | 5 | 32.73 | Asian | None | Drowning | No | No | Left | BA9, Vermis |
UMB-1349 | Autism | M | 5 | 39 | Caucasian | None | Drowning | No | No | Unknown | Vermis |
UMB-1174 | Autism | F | 7 | 14 | Caucasian | None | Seizure disorder | Yes | No | Unknown | BA9 |
UMB-4231 | Autism | M | 8 | 12 | African American | Olanzapine; galantamine | Drowning | No | Yes | Unknown | BA9, Vermis |
AN19511 | Autism | M | 8 | 22.16 | Caucasian | None | Cancer | Yes | No | Left | BA9, Vermis |
UMB-4721 | Autism | M | 8 | 16 | African American | None | Drowning | No | No | Unknown | Vermis |
AN16641 | Autism | M | 9 | 27 | Caucasian | Carbamazepine; methylphenidate; clonidine | Seizure disorder | Yes | Yes | Left | BA9 |
AN16115 | Autism | F | 11 | 12.88 | Caucasian | Carbamazepine; lamotrigine; dextroamphetamine; topiramate | Seizure/drowning | Yes | Yes | Right | Vermis |
UMB-4899 | Autism | M | 14 | 9 | Caucasian | None | Drowning | No | No | Unknown | BA9, Vermis |
AN17138 | Autism | M | 16 | 24 | Asian | Fexofenadine; buspirone; topiramate | Seizure disorder | Yes | No | Left | BA9, Vermis |
AN01570 | Autism | F | 18 | 6.75 | Caucasian | None | Seizure disorder | Yes | No | Right | BA9 |
AN00764 | Autism | M | 20 | 23.66 | Caucasian | Erythromycin gel; minocycline | MVA | No | Yes | Left | BA9 |
UMB-1638 | Autism | F | 20 | 50 | Caucasian | None | Seizure disorder | Yes | Yes | Unknown | BA9 |
AN09730 | Autism | M | 22 | 25 | Caucasian | Aripiprazole; lamotrigine; zonisamide | Aspiration | Yes | No | Left | BA9, Vermis |
AN08166 | Autism | M | 29 | 43.25 | Caucasian | Fexofenadine; ziprasidone HCl; carbamazepine | Seizure (suspected) | Yes | No | Left | BA9, Vermis |
AN12457 | Autism | F | 29 | 17.83 | Caucasian | Fluvoxamine | Seizure disorder | Yes | No | Left | BA9, Vermis |
AN11989 | Autism | M | 30 | 16.06 | Caucasian | None | Heart failure (congestive) | No | No | Left | BA9 |
AN08792 | Autism | M | 30 | 20.33 | Caucasian | Cisapride; clorazepate; sodium valproate; phenytoin; folic acid; primidone; phenobarbital; omeprazole; metoclopramide | Gastrointestinal bleeding | Yes | No | Left | BA9, Vermis |
UMB-5027 | Autism | M | 37 | 26 | African American | None | Obstruction of bowel due to adhesion | No | No | Unknown | BA9, Vermis |
AN06420 | Autism | M | 39 | 13.95 | Caucasian | None | Cardiac tamponade | No | No | Left | BA9, Vermis |
AN14613 | Autism | M | 39 | 22.75 | Caucasian | None | Sudden unexpected death | Yes | No | Unknown | BA9 |
AN17777 | Autism | F | 49 | 16.33 | Caucasian | Wafarin; venlafaxine; erythromycin; lansoprazole; risperidone; metformin; gabapentin; propranolol; levothyroxine | Pulmonary arrest | No | Yes | Left | BA9, Vermis |
AN01093 | Autism | M | 56 | 19.48 | Caucasian | Benztropine mesylate; haloperidol; lithium; chlorpromazine; alprazolam | Anoxic encephalopathy | Yes | No | Right | BA9, Vermis |
Children | Control | Autistic | Change | P -value | d | Â | |||||
Age ± SD (years) | 11.4 ± 5.22 | 9.5 ± 4.38 | ↓16.6% | ns | nd |  | |||||
PMI ± SD (years) | 20.6 ± 8.1 | 20.1 ± 9.94 | ↓2.4% | ns | nd |  | |||||
Gender | 7M | 8M:4F | nd | nd | nd | Â | |||||
Adults | Control | Autistic | Change | P- value | d | Â | |||||
Age ± SD (years) | 34.2 ± 13 | 33.3 ± 11.2 | ↓2.6% | ns | nd |  | |||||
PMI ± SD (years) | 20.9 ± 8.41 | 24.6 ± 11.1 | ↑17.7% | ns | nd |  | |||||
Gender | 9M:3F | 9M:3F | nd | nd | nd | Â | |||||