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Figure 2 | Molecular Autism

Figure 2

From: Impairment of fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling and its downstream cognates ras-related C3 botulinum toxin substrate 1, amyloid beta A4 precursor protein, striatal-enriched protein tyrosine phosphatase, and homer 1, in autism: a postmortem study in cerebellar vermis and superior frontal cortex

Figure 2

Expression of RAC1, APP, and homer 1 in the cerebellar vermis of subjects with autism and controls. (A) Mean RAC1/β-actin, APP 120 kDa/β-actin, APP 88/β-actin, and homer 1/β-actin ratios for controls (gray histogram bars) and people with autism (black histogram bars) are shown for the cerebellar vermis. (B) Mean RAC1/NSE, APP 120 kDa/NSE, APP 88/NSE, and homer 1/NSE ratios for controls (gray histogram bars) and people with autism (black histogram bars) are shown for the cerebellar vermis. Error bars express standard error of the mean. *P <0.05. RAC1, Ras-related C3 botulinum toxin substrate 1; amyloid beta A4 precursor protein; NSE, neuronal specific enolase.

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Molecular Autism

ISSN: 2040-2392