Table 1 Demographic data for human brain tissue samples
From: Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?
Casea | Diagnosis | CGG repeats | Age (years) | Postmortem interval (hours) | Cause of death | Central nervous system drug useb |
|---|---|---|---|---|---|---|
UMB-1421 | Fragile X | 563d, 297e | 69 | 17 | Cancer | NA |
UMB-1938 | Fragile X | NA | 62 | 26 | Hypertensive cardiovascular disease | NA |
UMB-4751 | Fragile X carrier | 88 | 21 | 5 | Pulmonary edema or pneumonia | Antiepileptics |
UMB-4806 | Fragile X | NA | 9 | 22 | Cardiac arrest | Clonidine |
UMB-5006 | Fragile X carrier | 150 | 85 | 5 | Complication of disorder | NA |
UMB-5319 | Fragile X | NA | 71 | 17 | Complication of disorder | NA |
UMB-4664 | Fragile X carrier | 100 | 71 | 3 | Complication of disorder | NA |
UMB-5212 | Fragile X carrier (FXTAS) | NA | 80 | 12 | Complication of disorder | NA |
1031-08-GP | Fragile X | 436 | 57 | 20 | Food choking | Antipsychotics |
JS-03 | Fragile X | NA | 25 | 16 | NA | NA |
1005-06-CB/XX | Fragile X | NA | 55 | - | NA | NA |
1018-10-RH | Fragile X | NA | 60 | 55 | NA | NA |
1031-09-LZ | Fragile X | 429d, 340 – 440e | 64 | 12 | Cancer | None |
1033-08-WS | Fragile X | > 339d | 78 | 18 | Chronic obstructive pulmonary disease or cardiac block | Antiepileptics |
UMB-1442 | Healthy | NA | 22 | 7 | Multiple injuries | NA |
UMB-5082 | Healthy | NA | 68 | 19 | Arteriosclerotic cardiovascular disease | None |
UMB-5123 | Healthy | NA | 61 | 24 | Arteriosclerotic cardiovascular disease | NA |
UMB-1103 | Healthy | NA | 21 | 7 | Accident, multiple injuries | NA |
UMB-1674 | Healthy | NA | 8 | 36 | Hyperthermia and drowning | NA |
UMB-5182 | Healthy | NA | 86 | 23 | Hypertensive cardiovascular disease | NA |
UMB-1104 | Healthy | NA | 35 | 12 | Accident, multiple injuries | Alcohol |
UMB-4593 | Healthy | NA | 33 | 8 | Cardiac arrhythmia | NA |
UMB-4598 | Healthy | NA | 45 | 6 | Dilated cardiomyopathy | NA |
UMB-4735 | Healthy | NA | 73 | 21 | Chronic obstructive pulmonary disease | NA |
UMB-5171 | Healthy | NA | 79 | 5 | Chronic obstructive pulmonary disease or peripheral vascular disease | None |
UMB-1039 | Healthy | NA | 49 | 9 | Accident, multiple injuries | NA |
UMB-1227 | Healthy | NA | 52 | 16 | Pulmonary embolism | NA |
UMB-1228 | Healthy | NA | 47 | 13 | Arteriosclerotic cardiovascular disease | NA |
UMB-1570 | Healthy | NA | 48 | 14 | Arteriosclerotic cardiovascular disease | NA |
UMB-1907 | Healthy | NA | 54 | 17 | Accident, multiple injuries | NA |
UMB-4915 | Healthy | NA | 49 | 5 | Arteriosclerotic cardiovascular disease | NA |
Number of subjects ( n ) | Diagnosis | Age (years) c | Postmortem interval (hours) c | |||
| Â | Â | Mean | Range | Mean | Range | |
14 | Fragile X (n = 10) or carrier (n = 4) | 58 | 9 to 85 | 17 | 3 to 55 | |
17 | Healthy | 49 | 8 to 86 | 14 | 5 to 36 | |