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Table 3 Two-by-two mixed model ANOVA [group by reward type] for the contrast correct feedback > baseline

From: Social and monetary reward processing in autism spectrum disorders

 

Cluster size (voxels)

F (Peak)

MNI co-ordinates (x,y,z)

BA and/or probability (ifavailable)

Main effect of reward feedback (MID > SID):

Frontal

    

Right inferior frontal gyrus p. orbitalis

36

17.96

42, 22, -12

45

Right paracentral lobule

35

17.51

10, -28, 64

4a (50%)

Left inferior frontal gyrus p. opercularis

27

15.79

−54, 14, 32

44 (60%)

Left superior medial gyrus

20

13.72

−4, 46, 30

32

Right anterior cingulate

23

15.63

4, 34, 20

24

Right middle cingulate

80

15.18

4, -30, 34

23

Left insula lobe

11

14.41

−32, 24, 4

47

Temporal

    

Right superior temporal gyrusa

81

20.44

66, -24, 6

22; TE 3 (40%)

Right superior temporal gyrus

29

15.78

54, -14, 4

48; TE 1 (70%)

Left superior temporal gyrus

12

14.45

−40, -32, 10

41; TE 1.1 (60%)

Right inferior temporal gyrus

17

16.74

52, -62, -12

37; HOC5 (V5) (10%)

Occipital

    

Left middle occipital gyrusa

834

42.68

−32, -94, 6

18 (20%); hOC3v (V3v) (20%)

Left calcarine gyrusa

103

18.49

−16, -74, 8

17 (80%)

Right calcarine gyrus

37

15.2

16, -70, 10

17 (90%)

Right fusiform gyrusa

1787

61.63

30, -66, -4

18 (10%)

Right fusiform gyrus

16

18.56

42, -46, -16

37

Left fusiform gyrusa

95

59.6

−28, -64, -12

19; hOC4 (V4) (10%)

Parietal

    

Right postcentral gyrus

34

20.58

62, -14, 30

3b (30%)

Left postcentral gyrus

10

14.4

−46, -24, 44

2 (80%); 3b (60%)

Left inferior parietal lobule

52

15.68

−34, -50, 56

SPL (7PC) (60%)

Left inferior parietal lobule

13

18.91

−54, -30, 38

2; IPC (PFt) (40%)

Left superior parietal lobule

45

17.72

−20, -48, 46

SPL (5 L) (20%)

Subcortical

    

Right caudate nucleusb

17

17.14

14, 8, 20

NA

Right caudate nucleus

12

15.24

16, 12, 0

NA

Left thalamus

15

13.9

−28, -34, 2

Th visual (18%); Temporal (11%)

Cerebellum

    

Right lobule VIIa crus1

16

14.91

42, -74, -38

72%

Main effect of group (ASD > CON):

Parietal

    

Left rolandic operculum

11

15.31

−50, 0, 8

43; OP 4 (30%)

Group by reward type interaction:

Parietal

    

Right angular gyrus

21

16.31

32, -64, 46

SPL (7P) (10%)

Left inferior parietal lobule

25

17.21

−32, -52, 44

40; hIP3 (30%)

Right postcentral gyrus

16

14.81

32, -64, 46

3b (60%)

Temporal

    

Right inferior temporal gyrus

47

20.91

52, -62, -14

37; hOC5 (V5) (10%)

Subcortical

    

Left caudate nucleusb

62

18.62

−18, -2, 24

NA

Cerebellum

    

Cerebellar vermis lobule VI

21

17.74

−2, -76, -16

71%

Right lobule VIIa crus 1

17

14.69

46, -66, -32

100%

  1. Results are reported at an uncorrected level of P <0.001 (extent threshold 10 voxels).
  2. aRegions surviving correction for multiple comparisons (FWE P <0.05) at the whole-brain cluster or peak level.
  3. bUsing anatomical small volume correction in a priori regions.