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Figure 3 | Molecular Autism

Figure 3

From: Loci nominally associated with autism from genome-wide analysis show enrichment of brain expression quantitative trait loci but not lymphoblastoid cell line expression quantitative trait loci

Figure 3

Histograms of expression quantitative trait loci enrichment analyses for Strict|All dataset. The gray histogram distributions represent the null distribution created by 1,000 lists of randomly ascertained SNPs drawn from the 1 M array platform and conditioned on minor allele frequency. The black dot represents the actual count of SNPs annotated as eQTL present in each tissue in the Strict|All Ancestry analysis. Significant enrichment of parietal eQTL (P <0.001), but not cerebellar (P <0.872) or LCL (P <0.110) eQTL was identified in the Strict|All dataset. eQTL: expression quantitative trait loci; LCL: lymphoblastoid cell line; SNP: single nucleotide polymorphism.

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Molecular Autism

ISSN: 2040-2392