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Figure 2 | Molecular Autism

Figure 2

From: Loci nominally associated with autism from genome-wide analysis show enrichment of brain expression quantitative trait loci but not lymphoblastoid cell line expression quantitative trait loci

Figure 2

Histograms of expression quantitative trait loci enrichment analyses for Spect|All analyses. The gray histogram distributions represent the null distribution created by 1,000 lists of randomly ascertained SNPs drawn from the 1 M array platform and conditioned on minor allele frequency. The black dot represents the actual count of SNPs annotated as eQTL present in each tissue in the Spectrum|All Ancestry analysis. We observed significant enrichment of parietal (P <0.004) and cerebellar (P <0.003) eQTL, but not LCL eQTL (P <0.502). eQTL: expression quantitative trait loci; LCL: lymphoblastoid cell line; SNP: single nucleotide polymorphism.

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