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Table 2 Genes with altered expressions in autism postmortem brains

From: Brain region-specific altered expression and association of mitochondria-related genes in autism

Gene

Anterior Cingulate Gyrus

Motor Cortex

Thalamus

 

Fold change

P value*

Fold change

P value*

Fold change

P value*

AIP b,d,e

  

−1.473

0.048

  

BCL2 a,b,j

1.356

0.045

    

DNAJC19 b,d,e

  

−1.868

0.037

−1.520

0.030

DNM1L i,j

−1.658

0.020

−1.603

0.045

  

HSP90AA1 b

    

1.662

0.044

LRPPRC i

−1.486

0.025

−1.530

0.018

  

MFN2 b,d,h,i

−1.446

0.021

    

MIPEP b,d,e

  

−2.003

0.012

  

MTX2 b

−1.795

0.044

−2.055

0.017

−2.511

0.002

NEFL i

−4.208

0.014

−2.935

0.025

−6.006

0.012

RHOT2 i

−1.338

0.019

    

SLC25A12 c

−2.112

0.013

−1.913

0.008

  

SLC25A14 c

−1.876

0.034

−1.924

0.010

  

SLC25A15 c

−1.402

0.036

    

SLC25A22 c

−2.061

0.007

    

SLC25A24 c

  

−1.690

0.008

−1.625

0.019

SLC25A25 c

    

1.830

0.044

SLC25A27 c

−2.132

0.025

−2.167

0.042

−2.644

0.026

SLC25A3 c

  

−1.668

0.020

  

SLC25A37 c

    

1.973

0.046

SLC25A4 c

−1.614

0.034

    

SLC25A5 c

  

−1.548

0.027

  

SOD2 j

    

3.919

0.036

TIMM17A g

−1.809

0.011

    

TIMM17B g

−1.601

0.006

    

TIMM23 g

  

−1.734

0.022

  

TIMM44 g

    

1.769

0.034

TIMM50 g

−1.513

0.045

    

TIMM8A g

−1.612

0.021

    

TIMM9 g

    

−1.940

0.010

TOMM20 f

−1.812

0.025

−1.745

0.017

  

TOMM22 f

−1.450

0.024

    

TOMM34 f

    

−1.995

0.002

TOMM70A f

−1.525

0.041

    

TP53 a,b,j

1.769

0.021

    

TSPO b,d

1.720

0.037

    
  1. aMembrane polarization and potential; bMitochondrial transport; cSmall molecule transport; dTargeting proteins to mitochondria; eMitochondrion protein import; fOuter membrane translocation; gInner membrane translocation; hMitochondrial fission and fusion; iMitochondrial localization; jApoptotic genes; *P values were calculated by t-test.