Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study

Table 2 Characteristics of the Early Markers for Autism study population^a

Characteristics	ASD (N= 84)		DD (N= 49)		GP (N= 159)		ASD vs. GP	ASD vs. DD	DD vs. GP
	n	%	n	%	n	%	P value	P value	P value
Gender							0.91	0.0003	<0.0001
Male	73	86.9	29	59.2	139	87.4
Female	11	13.1	20	40.8	20	12.6
Plurality							0.42	1.0	0.34
Singleton	81	96.4	47	95.9	156	98.1
Multiple	3	3.6	2	4.1	3	1.9
Parity								0.05	0.24
Primiparous	42	50.0	16	32.7	67	42.1	0.24
Multiparous	42	50.0	33	67.3	92	57.9
Mother's race							0.06	0.63	0.62
Caucasian	57	67.9	37	75.5	126	79.2
Asian	19	22.6	9	18.4	28	17.6
Other	6	7.1	3	6.1	5	3.1
Missing	2	2.4	0	0	0	0
Mother's ethnicity							0.0007	0.0001	0.17
Hispanic	20	23.8	28	57.1	73	45.9
Non-Hispanic	64	76.2	21	42.9	86	54.1
Mother's birth country							<0.0001	<0.0001	0.33
United States	45	53.6	16	32.7	71	44.7
Mexico	9	10.7	22	44.9	58	36.5
Other	30	35.7	11	22.4	30	18.9
Mean maternal age, years (±SD)	30.9 (5.2)		28.3 (5.2)		28.2 (5.5)		0.0003	0.006	0.87
Mean paternal age, years (±SD)	34.0 (6.3)		33.0 (7.9)		31.0 (6.5)		0.001	0.41	0.14
Mean last recorded maternal weight prior to blood draw, lb (±SD)	145.1(26.7)		149.1(38.7)		146.9 (33.8)		0.65	0.53	0.56

^aASD: autism spectrum disorder; DD: developmental delay; GP: general population.

ISSN: 2040-2392