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Table 1 Haplotype transmission disequilibrium results in the overall population across leucine-rich repeat transmembrane neuronal (LRRTM3).

From: Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry

LD block/Tagb

Haplotypea

TR

NT

OR

CI

P-value

Block 2 (rs716546-rs716547-rs9971243)

CCT

75

52

1.44

(1.01, 2.05)

0.0505

Block 2 (rs716546-rs716547-rs9971243)

CTC

2

10

0.20

(0.04, 0.91)

0.0386

rs6480245, rs12266823b

GA

44

84

0.52

(0.36, 0.75)

0.0005

rs6480245, rs12266823b

GC

242

186

1.30

(1.07, 1.58)

0.0078

  1. The analysis was performed within each linkage disequilibrium (LD) block for each gene and for the haplotype combinations from Haploview (selected by Tagger). Only haplotypes approaching or below the nominal significance threshold of P < 0.05 are shown.
  2. aHaplotypes only reported if there are more than 10 informative transmissions in total.
  3. bHaplotype combinations selected by Tagger.
  4. CI, confidence interval; NT, non-transmitted; OR, odds ratio; SNP, single nucleotide polymorphism; TR, transmitted.